Recent Advances in Gold Nanomaterials for Photothermal Therapy

Gold nanoparticle (AuNPs)-mediated photothermal therapy (PTT) has attracted increasing attention both in laboratory research and clinical applications. Due to its easily-tuned properties of irradiation light inside-out hyperthermia ability, it demonstrated clear advantages cancer over conventional thermal ablation. Despite this great advancement, the therapeutic efficacy AuNPs mediated PTT tumor treatment remains compromised by several obstacles, including low conversion efficiency, tissue penetration limitation excitation light, inherent non-specificity. In view rapid development PTT, we present an in-depth review major breakthroughs advanced gold nanomaterials for with emphasis on those from 2010 date. particular, current state knowledge based agents within a paradigm key structure-optical property relationships is presented order provide guidance design novel AuNP meet necessary functional requirements specific Furthermore, potential challenges future are also elucidated translation. It expected that will soon constitute markedly promising avenue cancer.